发明名称 |
INHIBITORS OF SERINE PROTEASE ACTIVITY, METHODS AND COMPOSITIONS FOR TREATMENT OF HERPES VIRUSES |
摘要 |
Novel compositions and methods of treating and preventing a viral infection are provided. A method of blocking a viral infection facilitated by a serine proteolytic (SP) activity is disclosed, which involves administering to a subject suffering or about to suffer from a viral infection a therapeutically effective amount of a substance having serine protease inhibitory activity or serpin activity. Among the substances found to be useful are alpha 1-antitrypsin (AAT), peptide derivatives from the carboxy terminal end of AAT and synthetic drugs mimicking the action of such substances. The invention is particularly well suited for checking a viral infection mediated by members of herpesviridae family.
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申请公布号 |
WO0051625(A1) |
申请公布日期 |
2000.09.08 |
申请号 |
WO2000US05557 |
申请日期 |
2000.03.03 |
申请人 |
THE TRUSTEES OF UNIVERSITY TECHNOLOGY CORPORATION |
发明人 |
SHAPIRO, LELAND |
分类号 |
A61K38/08;A61K38/55;A61K38/57;A61P31/22;(IPC1-7):A61K38/08 |
主分类号 |
A61K38/08 |
代理机构 |
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地址 |
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