| 摘要 |
<p>A soft-gelatin, extended gelatin composition has been found, which composition comprises a non-brittle shell forming material. The wet composition comprises: (a) 30-60 % by weight of a film-forming material, (b) 5-35 % by weight of a water-dispersible or water-soluble plasticizer, (c) 25-65 % by weight purified water, wherein the film-forming material comprises gelatin and gum acacia, with gum acacia accounting for 0.5-50 % by weight of the total amount of the film-forming material, a dried film having 3-12 % by weight of water formed from said composition having no reduced elasticity as compared to a film having the same proportions of the same water-dispersible or water-soluble plasticizer to the total weight of only gelatin film-forming material. A soft gelatin capsule may be provided comprising a fill and a shell, wherein the shell comprises the dried material formed from that composition. A process of manufacturing a filled soft gelatin capsule comprising a fill and a shell is also disclosed wherein a fill is provided to an encapsulation area where a sheet of soft gelatin material comprising the above described composition, eventually providing a dried capsule film composition of about 30-70 % by weight of film-forming material and 58-27 % by weight of water-dispersible or water-soluble plasticizer. The sheet of wet soft gelatin material encapsulates the fill by the rotary die encapsulation process to form a filled soft gelatin capsule, wherein the shell eventually comprises a dried film having less than about 20 % by weight of water, and the shell is formed from the composition, the shell having no reduced elasticity as compared to a shell having the same proportions of the same water-dispersible or water-soluble plasticizer to the total weight of only gelatin film-forming material.</p> |
