发明名称 |
Ribozymes targeting the MoMLV PSI packaging sequence and the HIV tat sequence |
摘要 |
A cell comprising a synthetic non-naturally occurring oligonucleotide compound comprises nucleotides whose sequence defines a conserved catalytic region and nucleotides whose sequence hybridizes with a predetermined target sequence within a MoMLV Psi packaging sequence on the HIV tat sequence. The catalytic region may be derived from a hammerhead ribozyme, a hairpin ribozyme a hepatitis delta ribozyme, an PNAase P ribozyme, a group I intron or a group II intron.
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申请公布号 |
US6114167(A) |
申请公布日期 |
2000.09.05 |
申请号 |
US19940310259 |
申请日期 |
1994.09.21 |
申请人 |
GENE SHEARS PTY., LTD. |
发明人 |
SYMONDS, GEOFFREY P.;SUN, LUN-QUAN |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):C12N5/10 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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