| 摘要 |
PROBLEM TO BE SOLVED: To obtain a nature-derived oral antibacterial agent having excellent antibacterial action on intraoral bacteria causing caries.periodontal disease and widely applicable to various foods and drinks and oral products by effectively utilizing an extract of seeds or leaves of Perilla frutescens crispa or Perilla ocimoides. SOLUTION: This oral antibacterial agent contains seeds or leaves of Perilla frutescens crispa or Perilla ocimoides as an active component. An alcohol extract of seeds or leaves of Perilla frutescens crispa or Perilla ocimoides is divided to ethyl acetate fraction and water-soluble fraction and the ethyl acetate fraction as the ethyl acetate layer may be used as the active component. As the seeds of Perilla frutescens crispa or Perilla ocimoides, defatted seeds of Perilla frutescens crispa or Perilla ocimoides may be used. The oral antibacterial agent contains luteolin, rosemarinus acid or their derivatives as active components. The foods and drinks or oral products contain this oral antibacterial agent. |
