| 摘要 |
PROBLEM TO BE SOLVED: To obtain a therapeutic agent having intestinal tract contraction inhibitory action, therefore useful in treating various diseases caused by intestinal tract motion abnormalities by including methoxyphenylethylphenoxydimethylaminopropylhydrogensuccinate hydrochloride. SOLUTION: This therapeutic agent comprises (±)-1- o-[2-(m-methoxyphenyl) ethyl]phenoxy}-3-(dimethylamino)-2-propylhydrogensuccinate hydrochloride (general name: sarpogrelate hydrochloride). This compound can be directly used as an active ingredient, however, it is preferable that the compound is formulated with pharmacologically and pharmaceutically acceptable additive(s) into a preparation. The above therapeutic agent can be administered orally or parenterally (pref. orally), and its daily dose is 0.5-50, pref. 1-30 mg/kg body weight/adult in terms of the active ingredient in the case of oral administration in the form of tablets, or the like.
|
