| 摘要 |
Genetically altered mesenchymal stem cells include nucleic acid that encodes an immune system suppressor polypeptide which inhibits an immune response to the mesenchymal stem cells in a recipient of the mesenchymal stem cells. Such cells are useful in treating or correcting tissue injury and/or tissue disorders such as connective tissue disorders. The immune system suppressor polypeptide includes complement restriction factors, and enzymes or proteins which, when expressed in a xenogeneic cell, cause the reduction of a xenogeneic epitope on the cell-surface of the xenogeneic cell. |
