NOUVEAUX ANALOGUES OPTIQUEMENT PURS DE LA CAMPTOTHECINE ET LEURS PROCEDES DE PREPARATION

摘要

The invention concerns in particular compounds of general formula (a) wherein: R1 represents a lower alkyl radical; R2, R3, R4 and R5 independently represent H, a halo radical or OSO2R10; R6, R7, R8, R9 and R10 represent different variable groups. Said topoisomerase-inhibiting compounds are particularly useful as anticancer medicines.