CO-ADMINISTRATION OF LUCANTHONE AND RADIATION FOR TREATMENT OF CANCER

摘要

Disclosed is a method of treating primary central nervous system tumors in a host comprising administering radiation to the host and administering lucanthone to the host; wherein the radiation and lucanthone are administered in amounts effective to cause the arrest or regression of the primary central nervous system tumor in the host. Also disclosed is a method of treating primary central nervous system tumors including inducing base damage to a tumor cell's DNA; and inhibiting excision repair of that damage by providing lucanthone to the cell.