发明名称 Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
摘要 The invention relates to a defined crystal modification of 8-cyano -1-cyclopropyl -7- (1S, 6S- 2,8- diazabicyclo [4.3.0] nonan-8-yl) -6-fluoro -1,4- dihydro -4-oxo-3- quinoline carboxylic acid, to methods for producing the same and to the use thereof in pharmaceutical formulations. The crystal modification can be distinguished from other crystal modifications of 8-cyano -1-cyclopropyl -7-(1S, 6S-2,8- diazabicyclo [4.3.0] nonan-8-yl) -6-fluoro -1,4-dihydro -4-oxo -3-quinoline carboxylic acid of formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram.
申请公布号 DE19908448(A1) 申请公布日期 2000.08.31
申请号 DE19991008448 申请日期 1999.02.26
申请人 BAYER AG 发明人 HIMMLER, THOMAS;RAST, HUBERT
分类号 A61K31/4709;A61P31/04;C07D471/04;(IPC1-7):C07D471/04;A61K31/47 主分类号 A61K31/4709
代理机构 代理人
主权项
地址