摘要 |
2-Aryl-1,3-ketoenol compounds (I) are prepared by reaction of a ketene compound (II) with a vinyl compound (III). Preparation of 2-aryl-1,3-ketoenol compounds of formula (I) comprises reaction of a ketene compound of formula (II) with a vinyl compound of formula (III), optionally in the presence of a diluent. W', X, Y', Z' = H, alkyl, aryl (optionally substituted), alkoxy, halo or haloalkyl; M = O, S or N-R; R = alkyl, aryl or arylalkyl; A = H, or alkyl, cycloalkyl, aryl or heteroaryl (all optionally substituted); B' = H, halo, or alkyl or cycloalkyl (all optionally substituted); and D' = H or optionally substituted alkyl; or D', A and the C atoms to which they are linked = an unsaturated, optionally substituted 5-8 membered ring; or D', B' and the C atoms to which they are linked = an unsaturated, optionally substituted 5-8 membered ring
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