发明名称 |
METHOD OF MODIFYING CYTOTOXIC CELLS AND USES THEREOF |
摘要 |
TALL-104 cells, and other cytotoxic T cell lines, may be modified to increase the cytotoxicity thereof, to enhance growth properties, and/or to provide a preferred phenotype, e.g., expression of cell surface antigens, function, e.g., change in cytokine production profile, by culturing the cells in an effective amount of IL-15, optionally followed by gamma irradiation to halt proliferation.
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申请公布号 |
WO0050569(A1) |
申请公布日期 |
2000.08.31 |
申请号 |
WO2000US04548 |
申请日期 |
2000.02.23 |
申请人 |
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY;SANTOLI, DANIELA;ROVERA, GIOVANNI;CESANO, ALESSANDRA |
发明人 |
SANTOLI, DANIELA;ROVERA, GIOVANNI;CESANO, ALESSANDRA |
分类号 |
A61K35/12;C12N5/0783;C12N5/09;(IPC1-7):C12N5/00;C12N5/02 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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