PROCESS OF CONVERTING TAXANES INTO BACCATIN III AND 10-DEACETYLBACCATIN III.
摘要
<p>A process for the preparation of a compound of formula (I) <IMAGE> comprising contacting a mixture containing at least one taxane compound having an ester linkage at the C-13 position with at least one borohydride reducing salt in a reaction solvent in the presence of a Lewis acid.</p>
申请公布号
GR3033069(T3)
申请公布日期
2000.08.31
申请号
GR20000400758T
申请日期
2000.03.27
申请人
NAPRO BIOTHERAPEUTICS, INC.
发明人
CARVER, DAVID, R.;PROUT, TIMOTHY, R.;EWALD, HERNITA, A.;HENDERSON, DONIA, L.