发明名称 PHARMACEUTICAL COMPOSITIONS CONTAINING A CRYSTALLINE FORM OF THE PROGESTAGEN-(17ALPHA)-17-HYDROXY-11-METHYLENE-19-NOR-PREGNA-4,15-DIEN-20-YN-3-ONE (ORG 30659) AND LACTOSE
摘要 <p>The invention resides in the use of crystalline (17α)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one (Org 30659) for the preparation of a pharmaceutical formulation which crystalline Org 30659 is in a crystal form C, having a melting point of 158.7 °C and an enthalpy ΔH of 71.9 mJ/mg which pharmaceutical formulation retains a content of Org 30659 of more than 90 % of the starting content of the pharmaceutical formulation after storage for 8 months under conditions of 40 °C and relative environmental humidity of 75 %.</p>
申请公布号 WO2000050041(A1) 申请公布日期 2000.08.31
申请号 EP2000000886 申请日期 2000.02.04
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