发明名称 PYRAZOLES AS ESTROGEN RECEPTOR MODULATORS
摘要 Estrogen receptor-modulating pyrazole compounds are described in addition to methods and compositions for treating or preventing estrogen receptor-mediated disorders. The compounds described have been found to have unexpected and surprising activity in modulating estrogen receptor activity. Thus, the compounds of the present invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimer's disease.
申请公布号 WO0007996(A3) 申请公布日期 2000.08.31
申请号 WO1999US17799 申请日期 1999.08.06
申请人 CHIRON CORPORATION;HUEBNER, VERENA, D.;LIN, XIAODONG;JAMES, IAN;CHEN, LIYA;DESAI, MANOJ;KRYWULT, BEATA;SINGH, RAJINDER;WANG, LIANG 发明人 HUEBNER, VERENA, D.;LIN, XIAODONG;JAMES, IAN;CHEN, LIYA;DESAI, MANOJ;KRYWULT, BEATA;SINGH, RAJINDER;WANG, LIANG
分类号 A61K31/415;A61K31/4155;A61K31/416;A61K31/4427;A61K31/4433;A61K31/454;A61K31/498;A61K31/5377;A61P5/32;A61P19/10;A61P25/28;A61P35/00;C07D231/12;C07D231/54;C07D231/56;C07D261/08;C07D261/10;C07D261/18;C07D261/20;C07D401/04;C07D401/06;C07D403/04;C07D409/04;C07D413/04;C07D413/12;C07D471/04;C07D498/04;(IPC1-7):C07D231/12;C07D231/18 主分类号 A61K31/415
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