PHARMACEUTICAL COMPOSITIONS OF TIZOXANIDE AND NITAZOXANIDE

摘要

A pharmaceutical composition containing as active agent at least one compound selected among the group consisting of formula (I) and formula (II). The active agent is preferably in the form of particles having a particle size smaller than 200 micrometer and a mean particle size of greater than 10 micrometer. The pharmaceutical compositions are preferably stabilized with at least one pharmaceutically acceptable acid. The pharmaceutical compositions are particularly useful for treatment of opportunistic infections in persons with compromised or suppressed immune systems, and in treatment of infections of trematodes.