Enteric formulations of proanthocyanidin polymer dietary supplements and methodsfor preparing same

摘要

The present invention provides for a method for preparing a proanthocyanidin enriched composition useful as a dietary supplement. The proanthocyanidin polymer composition can be synthesized by the method comprising the steps of precipitating Croton ssp latex by adjusting the pH of the latex; removing precipitated residue from the precipitated latex to produce a filtrate; concentrating the filtrate to obtain a retentate; and drying the filtrate, the filtrate being essentially free of anti-foaming agents. A further optional additional step includes removing additional taspine from the retentate by contacting said retentate with chromatographic media. A proanthocyanidin composition product made by this process is also described. Dietary supplements containing a proanthocyanidin polymer enriched composition as well as dietary supplements containing a proanthocyanidin polymer enriched composition and an additional herbal agent, e.g., ginger, cinnamon, and peppermint oil are also described.