| 发明名称 |
LTA4, hydrolase inhibitors |
| 摘要 |
The present invention provides compounds having the structureAr1-Q-Ar2-O-(CH2)n-Zand pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
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| 申请公布号 |
US6110944(A) |
申请公布日期 |
2000.08.29 |
| 申请号 |
US19970814899 |
申请日期 |
1997.03.12 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
CHEN, BARBARA BAOSHENG;CHEN, HELEN;RUSSELL, MARK ANDREW |
| 分类号 |
C07D295/12;A61K31/155;A61K31/4164;A61K31/4184;A61K31/445;A61K31/4453;A61P1/04;A61P11/06;A61P17/06;A61P29/00;A61P43/00;C07C255/12;C07C257/06;C07C257/14;C07C259/14;C07D211/62;C07D233/10;C07D233/18;C07D233/22;C07D235/12;C07D295/185;(IPC1-7):A61K31/445;C07D211/60;C07D207/04;C07C69/76 |
主分类号 |
C07D295/12 |
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