发明名称 The reaction product of alkaloids of Chelidonium maius L. with thiophosphoric acid triaziridide is used as radiation treatment medicine
摘要 The use of thiophosphorus derivatives of alkaloids of general Formula (I), for producing a medicament for the treatment or prevention of radiation injuries. Wherein; n is 1, 2 or 3; m is 1, 2 or 3; R1, R2 and R3 each independently hydrogen or methoxy, wherein R1 and R2 or R2 and R3 together may represent a methylene dioxy group; R4 is hydrogen, hydroxy or methyl; and If R6 is hydrogen, R5 and R7 together form the group represented by Formula (II); or, if R7 represents a methyl group, the group R5 and R6 is represented by Formula (III); and in positions 1, 8 and/or 2, 3 there may be a double bond; and A is a monovalent or the equivalent portion of the polyvalent anion, as well as their salts with pharmaceutically compatible acids.
申请公布号 NZ308024(A) 申请公布日期 2000.08.25
申请号 NZ19960308024 申请日期 1996.05.30
申请人 WASSYL NOWICKY 发明人 NOWICKY, WASSYL
分类号 A61K31/675;A61K;A61K31/66;A61K36/18;A61P9/00;A61P37/04;A61P39/00;A61P43/00;C07F9/564;(IPC1-7):A61K31/66 主分类号 A61K31/675
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