摘要 |
The use of thiophosphorus derivatives of alkaloids of general Formula (I), for producing a medicament for the treatment or prevention of radiation injuries. Wherein; n is 1, 2 or 3; m is 1, 2 or 3; R1, R2 and R3 each independently hydrogen or methoxy, wherein R1 and R2 or R2 and R3 together may represent a methylene dioxy group; R4 is hydrogen, hydroxy or methyl; and If R6 is hydrogen, R5 and R7 together form the group represented by Formula (II); or, if R7 represents a methyl group, the group R5 and R6 is represented by Formula (III); and in positions 1, 8 and/or 2, 3 there may be a double bond; and A is a monovalent or the equivalent portion of the polyvalent anion, as well as their salts with pharmaceutically compatible acids.
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