Diagnosis of onset of bovine leukemia virus (BLV) and the resistance thereto

摘要

The specification describes the diagnosis of onset of bovine leukemia caused by bovine leukemia virus (BLV). The method involves the identification of an individual carrying the amino acid sequence Val-Asp-Thr-Tyr as specified by the amino acid numbers 75 to 78 in the 'beta'1 domain of the bovine MHC Class II DR'beta' chain. Such an individual is judged to be predisposed to the onset of the disease. The resistance to the onset of bovine leukemia caused by BLV wherein an individual carrying the amino acid Val as the one specified by the amino acid number 78 in the 'beta'1 domain of the bovine MHC Class II DR'beta' chain may also be identified.