发明名称 |
AMPA receptor antagonist to treat dyskinesias associated with dopamine agonist therapy |
摘要 |
AMPA receptor antagonists such as 3-(2-chloro-phenyl)-2-[2-(6-diethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one, can be used for treating dyskinesias associated with dopamine agonist therapy in mammals. Specifically, AMPA can be used when the dopamine agonist therapy involves the administration of L-dopa, or L-dopa in combination with an inhibitor of peripheral dopadecarboxylase, such as carbidopa or benserazide.
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申请公布号 |
NZ331636(A) |
申请公布日期 |
2000.08.25 |
申请号 |
NZ19980331636 |
申请日期 |
1998.08.31 |
申请人 |
PFIZER PRODUCTS INC |
发明人 |
CHENARD, BERTRAND LEO;GREENAMYRE, JOHN TIMOTHY;MENNITI, FRANK SAMUEL;WELCH, WILLARD MCKOWAN |
分类号 |
A61K45/00;A61K31/135;A61K31/165;A61K31/198;A61K31/505;A61K31/517;A61P25/00;A61P25/14;A61P43/00;(IPC1-7):A61K31/505 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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