发明名称 AMPA receptor antagonist to treat dyskinesias associated with dopamine agonist therapy
摘要 AMPA receptor antagonists such as 3-(2-chloro-phenyl)-2-[2-(6-diethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one, can be used for treating dyskinesias associated with dopamine agonist therapy in mammals. Specifically, AMPA can be used when the dopamine agonist therapy involves the administration of L-dopa, or L-dopa in combination with an inhibitor of peripheral dopadecarboxylase, such as carbidopa or benserazide.
申请公布号 NZ331636(A) 申请公布日期 2000.08.25
申请号 NZ19980331636 申请日期 1998.08.31
申请人 PFIZER PRODUCTS INC 发明人 CHENARD, BERTRAND LEO;GREENAMYRE, JOHN TIMOTHY;MENNITI, FRANK SAMUEL;WELCH, WILLARD MCKOWAN
分类号 A61K45/00;A61K31/135;A61K31/165;A61K31/198;A61K31/505;A61K31/517;A61P25/00;A61P25/14;A61P43/00;(IPC1-7):A61K31/505 主分类号 A61K45/00
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