发明名称 |
Indole derivatives and their use as mcp-1 receptor antagonists |
摘要 |
The present invention relates to certain novel compounds, including their production, their formulation as pharmaceutical compositions, and their therapeutic uses. In particular, the invention discloses certain indole derivatives and their function as inhibitors of monocyte chemoattractant protein-1 (MCP-1) and RANTES induced chemotaxis. The invention also discloses the use of the novel compounds in the treatment of inflammatory disease. |
申请公布号 |
AU2304300(A) |
申请公布日期 |
2000.08.25 |
申请号 |
AU20000023043 |
申请日期 |
2000.01.31 |
申请人 |
ASTRAZENECA UK LIMITED |
发明人 |
ALAN WELLINGTON FAULL;JASON KETTLE |
分类号 |
A61K31/404;A61K31/407;A61K31/4178;A61K31/422;A61K31/5377;A61K31/541;A61P1/04;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P37/06;C07D209/22;C07D209/42;C07D403/12;C07D409/12;C07D413/12;C07D487/04 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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