METHODS FOR DETERMINING THE PRESENCE OF NUCLEIC ACID TARGET SEQUENCES AND APPLICATIONS THEREOF

摘要

Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined exogenous nucleic acid. Applications of those processes include the detectio n of single nucleotide polymorphisms, identification of single base changes, determination of viral load, genotyping, medical marker diagnostics, and the like.