发明名称 AKT COMPOSITIONS FOR ENHANCING SURVIVAL OF CELLS
摘要 This invention relates to methods and compositions for the treatment of apoptotic cell-death. In particular the invention relates to Akt molecules and their use in inhibiting apoptotic cell-death in cardiomyocytes, skeletal myocytes and/or vascular endothelial cells. In view of these discoveries, Akt molecules can be used to inhibit apoptotic cell-death of any of the foregoing cells, and in particular, to treat conditions (e.g., myocardial infarction) that result in increased apoptotic cell-death of cardiomyocytes, skeletal myocytes and/or vascular endothelial cells.
申请公布号 WO0020025(A9) 申请公布日期 2000.08.24
申请号 WO1999US22633 申请日期 1999.09.29
申请人 ST. ELIZABETH'S MEDICAL CENTER, INC. 发明人 WALSH, KENNETH
分类号 A61K38/27;A61K38/45;A61K45/00;A61P9/10;A61P21/00;A61P21/04;A61P43/00;C12N5/10;C12N15/09;G01N33/15;G01N33/50 主分类号 A61K38/27
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