| 发明名称 |
INHIBITORS OF SEPARIN, METHOD FOR IDENTIFYING THEM AND USES |
| 摘要 |
Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploid y in plants.
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| 申请公布号 |
CA2362794(A1) |
申请公布日期 |
2000.08.24 |
| 申请号 |
CA20002362794 |
申请日期 |
2000.02.14 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
PETERS, JAN-MICHAEL;NASMYTH, KIM;UHLMANN, FRANK;CLYNE, ROSEMARY;BUONOMO, SARA;WAIZENEGGER, IRENE |
| 分类号 |
C12N15/09;A01H5/00;A61K38/55;A61K45/00;A61P5/24;A61P35/00;A61P43/00;C07K14/39;C12N5/04;C12N9/99;C12Q1/00;C12Q1/37;(IPC1-7):A61K38/55 |
主分类号 |
C12N15/09 |
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