2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS

摘要

2-Amino-6-anilino-purine derivatives of formula (I) in which R1 is -S(O)k-NR6R7 or-N(aryl lower alkyl) carbamoyl or -NH-S(O)i-R8 or -NH-C(O)-R9; 9 is 1-5; These compounds inhibit p34<cdc2>/cyclin B<cdc13> kinase and protein tyrosine kinase pp60<c-src> and can be used for treatment of hyperproliferative diseases, for example tumour diseases, and diseases which respond to inhibition of the activity of protein tyrosine kinase pp60<c-src>, in particular osteoporosis.