发明名称 |
PRODUCTION OF HETEROLOGOUS POLYPEPTIDES FROM FRESHWATER CAULOBACTER |
摘要 |
A method is provided for screening <u>Caulobacter</u> suitable for use as host organisms for secretion of heterologous polypeptides. Such <u>Caulobacter</u> have a transport protein homologous to one of the type I transport proteins known in <u>C. crescentus</u>. DNA constructs are also provided which code for a chimeric protein of which the C-terminus is a secretion signal of a <u>Caulobacter</u> surface layer protein, other than from <u>C. crescentus</u>. Bacterial cells containing, or which express such DNA constructs and which may secrete the resulting protein, are also provided.
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申请公布号 |
WO0049163(A1) |
申请公布日期 |
2000.08.24 |
申请号 |
WO2000CA00173 |
申请日期 |
2000.02.21 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA;SMIT, JOHN |
发明人 |
SMIT, JOHN |
分类号 |
C12N15/09;C07K14/195;C07K14/21;C12N1/21;C12N15/21;C12N15/74;C12Q1/02;C12Q1/68;C12R1/01;(IPC1-7):C12N15/74;C12N15/31;C12N15/62;C12Q1/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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