| 摘要 |
A wound closure system for closing a wound on a patient comprises an elongated flexible backing strip having opposite ends, first and second surfaces facing away from one another and a length and width sufficient to secure facing edges of the wound in close juxtaposition to one another, the backing strip comprising a first portion disposed between the ends and adapted to overlie the facing edges of the wound, and second and third portions disposed on either side of the first portion and each provided with a predetermined number of spaced-apart apertures extending through the backing strip from one surface thereof to the other; and a first pressure-sensitive adhesive coated on at least part of the first surface of the backing strip including the second and third portions thereof, to adhere at least the second and third portions of the backing strip to the patient with the facing edges of the wound being in close juxtaposition. A first protective member is removably attached to the backing strip and covers the pressure-sensitive adhesive. The wound closure system of the invention further includes a flowable, moisture-curable surgical adhesive for application into the apertures to strengthen the adhesion of the second and third portions of the backing strip to the patient. After removal of the protective member to expose the pressure-sensitive adhesive, application of the backing strip with the exposed pressure-sensitive adhesive onto the patient to secure the facing edges of the wound in close juxtaposition and application of the surgical adhesive into the apertures, the surgical adhesive flows through the apertures and upon curing forms discrete bonding sites cooperating with the backing strip to maintain the facing edges of the wound in close juxtaposition without the cured adhesive adversely affecting the flexibility of the backing strip.
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