发明名称 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives and a process for the preparation thereof
摘要 The present invention relates to the compound of formulae and to a process for the manufacture of compounds of the general formula which are ligands for the metabotropic glutamate receptors of group II, wherein T is tritium; R1 is hydroxy, lower alkoxy, lower alkenyloxy, benzyloxy, hydrogen, deuterium or tritium; R11 is hydrogen, deuterium or tritium, hydroxy or amino, and R2 is hydrogen or tritium, or R1 and R2 form a bond.
申请公布号 US6107342(A) 申请公布日期 2000.08.22
申请号 US19990385935 申请日期 1999.08.30
申请人 HOFFMANN-LA ROCHE INC. 发明人 ADAM, GEO;HUGUENIN-VIRCHAUX, PHILIPPE NICOLAS;MUTEL, VINCENT;STADLER, HEINZ;WOLTERING, THOMAS JOHANNES
分类号 A61K31/00;A61K31/196;A61P25/00;A61P25/18;C07C227/16;C07C227/32;C07C229/50;C07C247/14;(IPC1-7):A61K31/195;C07C61/28;C07C247/00 主分类号 A61K31/00
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