发明名称 DISINTEGRABLE PARTICLE
摘要 PROBLEM TO BE SOLVED: To obtain disintegrable particles comprising water-insoluble aggregated primary particles, having a specific ratio of bulk specific gravity to true specific gravity and good in feeling of use, massage feeling and disintegrating properties. SOLUTION: These disintegrable particles comprise at least partially water- insoluble aggregated primary particles in 0.1-0.6 (bulk specific gravity)/(true specific gravity) ratio and are capable of disintegrating the aggregation by reducing the concentration of water-soluble salts in an aqueous solution containing the water-soluble salts. The disintegrable particles are preferably obtained by bonding and aggregating the water-insoluble primary particles with a water-soluble binder and the binder preferably contains at least one kind of binder component selected from the group consisting of a carboxylic acid-modified polyvinyl alcohol, a sulfonic acid-modified polyvinyl alcohol and a carboxymethyl cellulose salt. The average particle diameter of the disintegrable particles is preferably 125-800μm. The water-soluble binder is preferably used in an amount of 0.75-25 wt.% based on the weight of the primary particles.
申请公布号 JP2000229807(A) 申请公布日期 2000.08.22
申请号 JP19990034679 申请日期 1999.02.12
申请人 KAO CORP 发明人 NAKAMURA MAMORU;MEIWA YOSHIHEI;HASEBE YOSHIHIRO
分类号 A61K9/16;A61K8/00;A61K8/73;A61Q19/10;(IPC1-7):A61K7/00 主分类号 A61K9/16
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