发明名称 COSMETIC
摘要 PROBLEM TO BE SOLVED: To obtain a cosmetic which maintains the original hyaluronic acid structure present in an organism, is excellent in safety and biocompatibility, improves its retentivity on the skin and promotes beauty effects by including a gel formed by a specific hyaluronic acid alone. SOLUTION: This cosmetic contains a gel formed by a hyaluronic acid alone with poor solubility in a neutral aqueous solution. It is preferable that the gel has a dissolution rate of >=50% for 12 h in a neutral 37 deg.C aqueous solution, the solubilized hyaluronic acid formed by treating a hyaluronic acid gel under the condition of the promoting acid hydrolysis of hyaluronic acid has branched structure, the hyaluronic acid thus solubilized partially contains a molecular weight fraction with a branching degree of >=0.5, and furthermore, the above gel is a kind selected from the group consisting of sheet-like, crushed and fluid ones.
申请公布号 JP2000229837(A) 申请公布日期 2000.08.22
申请号 JP19990035690 申请日期 1999.02.15
申请人 DENKI KAGAKU KOGYO KK 发明人 MAEDA KAZUAKI;ARAI KAZUHIKO
分类号 A61K8/72;A61K8/00;A61K8/02;A61K8/73;A61Q19/00;(IPC1-7):A61K7/48;A61K7/00 主分类号 A61K8/72
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