发明名称 |
Dopamine receptor antagonists |
摘要 |
This invention provides a novel class of oxadiazolyl piperidines which exhibit a high binding affinity for dopamine ligands. The compounds of the invention display selectivity for the dopamine D4 receptor over the dopamine D2 receptor. Preferably, these compounds act as dopamine antagonists, which are useful in the treatment of psychotic disorders.
|
申请公布号 |
US6107313(A) |
申请公布日期 |
2000.08.22 |
申请号 |
US19980165505 |
申请日期 |
1998.10.02 |
申请人 |
COMBICHEM, INC. |
发明人 |
WILLIAMS, JOHN;LAVRADOR, KARINE |
分类号 |
C07D413/04;C07D413/14;(IPC1-7):C07D413/04;A61K31/454 |
主分类号 |
C07D413/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|