(1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

The invention relates to compounds of formula (I) and to the salts thereof with mineral or organic acids, the solvates and/or hydrates thereof, exhibiting a high affinity and high selectivity with respect to human NK1 receptors of substance P. The invention also relates to a method for the production thereof, intermediate compounds of formula (VII) useful in the production thereof, pharmaceutical compositions containing said products and the use thereof in the production of medicaments to treat all pathologies involving substance P and NK1 human receptors.