发明名称 LACTAM INHIBITORS OF FXA AND METHOD
摘要 Lactam inhibitors are provided which have structure (I) wherein X is (2) or (3), Y is O or S and R4 is (4), R7O- or R8, and R1, R2, R3, R5, R6, R7, and R8, are as defined herein. These compounds are inhibitors of Factor Xa and thus are useful as anticoagulants. A method for treating cardiovascular diseases associated with thromboses is also provided.
申请公布号 CA2361919(A1) 申请公布日期 2000.08.17
申请号 CA20002361919 申请日期 2000.01.27
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 BISACCHI, GREGORY S.;SEILER, STEVEN M.;LAWRENCE, R. MICHAEL
分类号 C07D223/12;A61K31/55;A61K38/00;A61P7/02;A61P9/00;A61P43/00;C07D487/04;C07K5/06;C07K5/078;(IPC1-7):C07D223/06;C07D401/02;C07D403/02;A61K31/442;A61K31/496 主分类号 C07D223/12
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