| 摘要 |
<p>The present invention is directed to a method for detecting the presence or absence of a variant nucleotide at each of a plurality of different target sequence in a nucleic acid containing sample by use of a multiplex amplification method that utilises a plurality of ARMSTM-allele specific amplification primers possessing non-amplifiable tails in conjunction with an oligonucleotide array for detection amplification of variant nucleic acid sequences. The invention is of particular use in fingerprinting and genome typing, including single nucleotide polymorphism typing, and clinical diagnosis.</p> |
