摘要 |
<p>Compounds represented by general formula (1) and salts thereof; and novel oligonucleotide analogues prepared by using the same as the intermediate and exhibiting stable and excellent antisense activities and so on, wherein R?1 and R2¿ are each independently hydrogen, a hydroxyl-protecting group, a phosphoric acid group, or -P(R3)R4 (wherein R?3 and R4¿ are each independently C¿1?-C5 cyanoalkoxy, amino substituted with C1-C4 alkyl, or the like); A is C1-C4 alkylene; and B is optionally substituted purin-9-yl or 2-oxopyrimidin-1-yl.</p> |