| 发明名称 |
CRYSTAL STRUCTURE OF cPLA2, AND METHODS OF IDENTIFYING AGONISTS AND ANTAGONISTS USING SAME |
| 摘要 |
The present invention provides for crystalline cPLA2. The crystal structure of cPLA2 has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of cPLA2 activity and membrane binding using such models are also disclosed.
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| 申请公布号 |
WO0047763(A1) |
申请公布日期 |
2000.08.17 |
| 申请号 |
WO2000US03745 |
申请日期 |
2000.02.14 |
| 申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
DESSEN, ANDREA;SOMERS, WILLIAM, S.;STAHL, MARK, L.;SEEHRA, JASBIR, S. |
| 分类号 |
G01N33/50;C12N9/16;C12N9/20;C12N15/09;G01N33/15;G06F17/30;(IPC1-7):C12Q1/34 |
主分类号 |
G01N33/50 |
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