Dictyostelium dipeptidylaminopeptidase, process of its preparation and use

摘要

In the present invention there is disclosed Dictyostelium dipeptidylaminopeptidase process of preparation and use thereof. The dipeptidylaminopeptidase is obtained by isolation and purification from cellular slime mold, Dictyostelium discoideum. The dDAP enzyme has an activity, which is somewhat similar to both DAP-I and DAP-III from this organism, however it differs highly from them by its physical and other enzymatic characteristics. The dDAP enzyme can be used for removing dipeptides from the N-terminus of recombinantly produced precursor proteins or peptides.