Nickel catalyzed addition of -NH- containing compounds to vinyl and aryl halides

摘要

PCT No. PCT/US97/11521 Sec. 371 Date Dec. 29, 1998 Sec. 102(e) Date Dec. 29, 1998 PCT Filed Jun. 30, 1997 PCT Pub. No. WO98/00399 PCT Pub. Date Jun. 8, 1998A process for producing unsaturated nitrogen containing compounds such as enamides, enamines and aryl amineslamides is disclosed. A vinyl halide or aryl halide is reacted with an -NH- containing compound in the presence of a catalytic amount of a catalyst precursor composition comprising a zero-valent nickel and an organophosphine or carbene ligand. One step coupling of vinyl halides and aryl halides with -NH- containing compounds is made possible by practice of the invention.