| 发明名称 |
Modified HGP-30 heteroconjugates, compositions and methods of use |
| 摘要 |
A heteroconjugate is formed by linking a T cell binding ligand (TCBL) such as Peptide J of beta -2 microglobulin to a modified HGP-30 antigentic peptide fragment of p17 gag peptide, such as. for example ATL YSV HQR IDV KDT KEA LEK IEE EQN KS (SEQ ID NO: 5) The heteroconjugate is effective in eliciting a THI directed immune response and provides a vaccine composition for treating or preventing AIDS.
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| 申请公布号 |
US6103239(A) |
申请公布日期 |
2000.08.15 |
| 申请号 |
US19960695304 |
申请日期 |
1996.08.09 |
| 申请人 |
CEL-SCI CORPORATION |
发明人 |
ZIMMERMAN, DANIEL H.;SARIN, PREM S. |
| 分类号 |
A61K38/00;A61K39/00;A61P31/18;A61P37/04;C07K14/16;C07K14/74;C07K16/00;C07K16/10;C07K19/00;(IPC1-7):A61K39/21 |
主分类号 |
A61K38/00 |
| 代理机构 |
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