| 发明名称 |
Inhibiting protein interactions |
| 摘要 |
The invention discloses methods of inhibiting direct binding of Ras with Raf and screening methods to identify compounds which inhibit direct binding of Ras to Raf, Raf activation, and cell proliferation.
|
| 申请公布号 |
US6103692(A) |
申请公布日期 |
2000.08.15 |
| 申请号 |
US19970814836 |
申请日期 |
1997.03.11 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION;GEN HOSPITAL CORP |
发明人 |
AVRUCH, JOSEPH;LUO, ZHUJUN;MARSHALL, MARK S. |
| 分类号 |
A61K38/00;A61K45/00;A61P35/00;C07K5/04;C07K7/04;C07K14/435;C07K14/82;C12N5/06;C12N9/12;C12N15/09;C12Q1/02;C12Q1/48;G01N33/15;G01N33/50;G01N33/566;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
