发明名称 METHOD FOR STABILIZING PROTEIN IN URINE, STABILIZER, AND IMMUNOLOGICAL ASSAY USING THE SAME
摘要 PROBLEM TO BE SOLVED: To suppress the rise of measured values in the vicinity of neutral to alkali regions by having a bicarbonate compound and an azide and/a chelating agent contained in a urine sample, as necessary. SOLUTION: 50-1,000 mM, preferably 100-200 mM, more preferably 100 mM of a bicarbonate compound is to be contained in a urine sample. When the content of a bicarbonate compound becomes equal to 50 mM or less, sufficient stabilizing effects are not obtained in an acid region. When it contrary exceeds 1,000 mM, further stabilizing effects are not obtained, and dissolvability becomes inferior. By adding an azide in addition to a bicarbonate compound, it is possible to improve the effects of stabilizing protein in urine in the vicinity of a neutral region especially due to urinary sediment. Sediment is generally formed in a neutral region in a urine sample, and measured values rise with this. This sediment is formed by factors such as the types and concentration of salts contained in urine and pH. It is possible to prevent the formation of sediment by having a chelating agent contained in a urine sample.
申请公布号 JP2000221190(A) 申请公布日期 2000.08.11
申请号 JP19990023492 申请日期 1999.02.01
申请人 EIKEN CHEM CO LTD 发明人 SAKABE KAZUFUMI;KUBOTA NOBUYUKI
分类号 G01N33/48;G01N33/493;G01N33/53;(IPC1-7):G01N33/493 主分类号 G01N33/48
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