发明名称 |
NOUVEAUX DERIVES DE PIPERIDINE, PROCEDE POUR LEUR OBTENTION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT |
摘要 |
The invention relates to compounds of formula (I) and to the salts thereof with mineral or organic acids, the solvates and/or hydrates thereof, exhibiting a high affinity and high selectivity with respect to human NK1 receptors of substance P. The invention also relates to a method for the production thereof, intermediate compounds of formula (VII) useful in the production thereof, pharmaceutical compositions containing said products and the use thereof in the production of medicaments to treat all pathologies involving substance P and NK1 human receptors.
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申请公布号 |
FR2789390(A1) |
申请公布日期 |
2000.08.11 |
申请号 |
FR19990004429 |
申请日期 |
1999.04.07 |
申请人 |
SANOFI |
发明人 |
DUCOUX JEAN PHILIPPE;EDMONDS ALT XAVIER;GUEULE PATRICK;PROIETTO VINCENZO |
分类号 |
A61K31/45;A61K31/4545;A61P1/00;A61P1/04;A61P1/08;A61P9/00;A61P11/00;A61P11/08;A61P13/00;A61P13/02;A61P17/00;A61P25/00;A61P25/04;A61P25/06;A61P25/22;A61P25/24;A61P29/00;A61P37/00;A61P43/00;C07D211/00;C07D211/26;C07D211/30;C07D211/34;C07D267/00;C07D295/03;C07D413/06;(IPC1-7):C07D401/06;A61K31/454;A61K31/496 |
主分类号 |
A61K31/45 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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