| 发明名称 |
GENETICALLY ENGINEERED RETROVIRAL VECTOR PARTICLES CAPABLE OF INFECTING NON-DIVIDING CELLS |
| 摘要 |
The present invention is a method of generating retro- viral vector particles derived from retroviruses and capable of transducing therapeutic genes into non-dividing cells. Mutations made in the retroviral matrix protein (MA) enable infection of non-dividing cells.
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| 申请公布号 |
CA2360858(A1) |
申请公布日期 |
2000.08.10 |
| 申请号 |
CA20002360858 |
申请日期 |
2000.02.02 |
| 申请人 |
THOMAS JEFFERSON UNIVERSITY |
发明人 |
DORNBURG, RALPH |
| 分类号 |
A61K48/00;C12N15/48;C12N15/867;(IPC1-7):C12N15/48;C12N15/63;C12N15/64 |
主分类号 |
A61K48/00 |
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