发明名称 |
NOVEL BETULINIC ACID DERIVATIVES, PROCESSES FOR PREPARING SUCH DERIVATIVES AND ITS USE AS CANCER GROWTH INHIBITORS |
摘要 |
The invention relates to novel betulinic acid derivatives of structural formula having modifications at C2, C3, C17, C20 and/or C29 positions, said derivatives being useful as inhibitors of tumor/cancer cells; process for preparation of the said derivatives; pharmaceutical compositions comprising said derivatives useful in the treatment of ovarian, colon, lung, laryngeal, prostrate cancer, leukemia, lymphoma and a method of treatment of ovarian, colon, lung, laryngeal and prostrate cancer in mammals using said derivatives or compositions. |
申请公布号 |
WO0046235(A1) |
申请公布日期 |
2000.08.10 |
申请号 |
WO1999IN00065 |
申请日期 |
1999.11.17 |
申请人 |
DABUR RESEARCH FOUNDATION;RAMDOSS, SUNDER;JAGGI, MANNU;SIDDIQUI, MOHAMMAD, JAMSHED, AHMED;KHANNA, ACHLA, BEHL |
发明人 |
RAMDOSS, SUNDER;JAGGI, MANNU;SIDDIQUI, MOHAMMAD, JAMSHED, AHMED;KHANNA, ACHLA, BEHL |
分类号 |
A61P1/00;A61K31/216;A61K31/22;A61K31/255;A61P11/00;A61P11/04;A61P13/08;A61P15/08;A61P35/00;A61P35/02;C07B61/00;C07C51/367;C07C51/373;C07C62/06;C07C62/24;C07C67/10;C07C67/14;C07C69/003;C07C69/013;C07C69/757;C07C227/08;C07C229/50;C07C241/02;C07C243/22;C07C249/02;C07C249/08;C07C249/16;C07C251/18;C07C251/44;C07C251/84;C07C303/28;C07C309/66;C07C309/73;C07J63/00 |
主分类号 |
A61P1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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