摘要 |
<p>Method of producing 4-chloropyrimidine derivatives of formula (I) wherein, R1 is chlorine, CH3S- or a radical (a); and R2 is chlorine or CH3O- by chlorination of a compound of formula (II), wherein R3 signifies OH or CH3O-; and R4 signifies OH, CH3S- or SH, in the presence of an inert solvent and at least one catalyst, as well as the use of these compounds of formula (I) in the production of 7[(4,6-dimethoxy-pyrimidin-2-yl)thio]-3-methylphthalide.</p> |