TRANSGENIC ANIMAL SHOWING VASCULAR TISSUE-SPECIFIC EXPRESSION OF ANGIOTENSIN II2 RECEPTOR

摘要

A transgenic animal characterized by showing vascular tissue-specific expression of angiotensin II2 receptor and its descendents; a method for constructing this transgenic animal and its descendents; a recombinant gene for constructing the transgenic animal which contains a promoter region originating in a protein gene expressed in a vascular tissue and an angiotensin II2 receptor gene; a vascular tissue piece or a vascular cell originating in the transgenic animal characterized by showing vascular tissuespecific expression of angiotensin II2 receptor; and a method for analyzing the vascular physiological function and/or blood pressure regulatory function of angiotensin II2 receptor in vitro by using the above-described transgenic animal, vascular tissue or vascular cell.