发明名称 |
Transdermales therapeutisches System mit einer selbstklebenden Matrix, enthaltend organische Säure-Additionssalze von Alkaloiden des Morphin- bzw. Morphinantyps |
摘要 |
The invention relates to a transdermal therapeutic system (TTS) comprising a support layer which is impermeable to the active ingredient, a self-adhesive matrix consisting of a cationic base polymer and a detachable protective film on the side facing the skin. As active ingredient the matrix contains organic acid addition salts of morphine alkaloids on the basis of a water-soluble polyaminomethacrylate salt containing fatty acids. The invention is characterized in that a sparingly water-soluble copolymer of acrylic and methacrylic acid esters with a comparatively low quaternary content of ammonium groups which form a salt with inorganic acids is admixed to the cationic base polymer.
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申请公布号 |
DE19901085(A1) |
申请公布日期 |
2000.08.10 |
申请号 |
DE19991001085 |
申请日期 |
1999.01.14 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME AG |
发明人 |
KOCH, ANDREAS;MATUSCH, RUDOLF;ADAM, BERND;ASMUSSEN, BODO |
分类号 |
A61K9/70;A61K31/485;A61K47/12;A61K47/32;A61K47/34;A61P25/04;A61P25/30;(IPC1-7):A61L15/44;A61L15/58 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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