| 摘要 |
organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to substituted arylthioalkylthio-pyridines of the formula (I) where R1-R4 mean hydrogen atom; R5 is hydrogen atom, (C1-C4)-alkyl or (C1-C4)-alkoxyl; R6 means cycle substituted by R8 and R9 that is taken among the group including benzene, thiazole, imidazole, triazole, tetrazole, thiadiazole, pyridine, pyridine-N-oxide, pyrimidine and benzimidazole; R7,R9,R11,R12 mean hydrogen atom or (C1-C4)-alkyl; R8 is hydrogen atom, NH2-group or (C1-C4)-alkyl possibly substituted with R10; m = 2-4; n, p, q = 0. Salts of synthesized compounds are effective for control of bacterium Helicobacter. EFFECT: improved method of synthesis, valuable antibacterial properties. 10 cl, 2 tbl, 24 ex |
