发明名称 |
TRANSGENIC MOUSE EXPRESSING GREEN FLUORESCENT PROTEIN IN ASTROCYTES |
摘要 |
A transgenic mammal, specifically a mouse, containing in its genome a humanized mutant of green fluorescent protein operably linked to the glial fibrillary acidic protein promoter is provided. The mouse can be used to assay the effects of systemic or topical administration of neurotoxins and also to assay the effects of physical damage to neural tissue.
|
申请公布号 |
WO0002997(B1) |
申请公布日期 |
2000.08.10 |
申请号 |
WO1999US15759 |
申请日期 |
1999.07.08 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
MESSING, ALBEE;ZHUO, LANG;MURPHY, CHRISTOPHER, J. |
分类号 |
A01K67/027;C07K14/475;C12N15/85;(IPC1-7):C12N15/85;C12N5/10;C12N5/06;C07K14/435;A61K49/00 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|