| 摘要 |
In the presence of a metal catalyst such as a samarium compound, an oxime ester compound shown by the formula (1): wherein R1, R2, and R3 are the same or different from each other, and each represents a non-reactive atom or a non-reactive organic group; and R2 and R3, together with the adjacent carbon atom, may bond together to form a ring is reacted with a cyanogenation agent such as an alpha -cyanohydrin compound (e.g., acetone cyanohydrin) to form an alpha -aminonitrile derivative. By hydrolyzing the alpha -aminonitrile derivative, the corresponding alpha -amino acid or a salt thereof can be obtained. According to the above processes, an alpha -aminonitrile derivative and an alpha -amino acid can be obtained in high yields.
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